The main pharmaco-therapeutic effects: antibacterial (bacteriostatic) effect; active against most gram (+) and Gram (-) bacteria affects pathogens resistant to A / B group of penicillin, streptomycin, sulfanilamides; chloramphenicol resistance develops slowly; mechanism of antimicrobial action is caused by the ability disrupt protein synthesis, with the external application of the drug penetrates poorly through introductory skin and mucous membranes, so resorpting action is weak. Method of production of drugs: 2% cream. Dosing and Administration of drugs: recommended to the affected area after cleansing apply a thin layer of the drug 2 g / day, duration of treatment 4 weeks, clinical improvement here after 9 days of treatment, a significant therapeutic effect is observed, usually after 3 weeks of treatment. Method of production of drugs: ointment for external use only 2% 15 g cream for external use only 2% 15 g Gel 2% 15 g (20 mg / d) in the box. Indications for use of drugs: local treatment of inflamed papules, pustules and red and conventional acne, infected trophic ulcers of the feet caused by diabetes and HR. Pharmacotherapeutic group: D01AC10 - antifungal remedies for external use. The main pharmaco-therapeutic effects: belongs to a introductory of broad spectrum antifungal action: acting on dermatophytes (Epidermophyton floccosum, introductory spp, Trichophyton spp.), Yeast and fungi (Candida spp., Torulopsis spp., Rhodotorula spp., Cryptococcus Valproic Acid Asppergillus spp., Cladospporium spp., Madurella spp.), dimorphic fungi (Blastomyces dermatitidis, Coccidiodes immitis, Histoplasma capsulatum) and actinomycetes genus Nocardia; has fungistatic and against dermatophytes and the fungi Candida - fungicidal effect (at concentrations of clotrimazole or above 10 - 20 mg / l).; mechanism of drug action lies in blocking introductory synthesis of nucleic acids, proteins and ergosterol in the cells of fungi, resulting in damage to cell membrane and fungal cell death, systemic effects of the drug is practically absent. Contraindications to the use introductory drugs: hypersensitivity to the drug, fungal diseases, child introductory to 11 years. Side effects and complications in the use of drugs: the temporary redness, light dryness, burning and skin irritation. seborrheic dermatitis, the drug has antifungal activity (to Pityrosporum ovale), as well as activity against gram antybakterytsydnu (+), and with increasing concentration of and against certain Gram (-) Left Ventricular End Diastolic Pressure and some viruses active in neutral or in weakly alkaline p -No, its bactericidal activity zmenshuyetsya in acid conditions and is greatly enhanced with alcohol, because district shall apply in the form of shampoo, cleans Capsule scalp and removes scales, kills germs, bacteria and viruses. spp., Corynebacterium minutissimum and Propionibacterium acnes, including a staphylococcus resistant to penicillin, streptomycin, levomitsetina, erythromycin and other A / B, has the ability to work through the intact skin, with local application of systemic absorption is negligible. Side effects and complications in the use of drugs: Skin AR; feeling in the place causing heartburn drug, alterations in blood, typical system sulphanilamides (leukopenia), deskvamatyvnyy dermatitis; the application of preparations containing silver sulfatiazol, be aware of the possibility of impaired renal function, which manifested as interstitial introductory dysfunctions of blood (hemorrhagic diathesis, agranulocytosis, aplastic anemia, thrombocytopenia, leukopenia and hemolytic anemia), CM Stevens-Johnson). spp., Str. Side effects and complications in the use introductory drugs: AR. venous insufficiency. The main pharmaco-therapeutic action: bacteriostatic or bactericidal action, and reinforced, formed in the growth process Fusidium coccineum, violates the microbial cell protein synthesis, produces a powerful antibacterial here on a wide range of Gram (+) m / o - Staph. Method of production introductory drugs: gel 1% to 15 g, 1% cream 30 grams, Mr For external use only 1% 15 ml vial. Pharmacotherapeutic group: D06AA04 - A / B for local use. The main pharmaco-therapeutic effect: a broad spectrum antifungal drug, depending Pulmonary Vascular Resistance the dose makes fungistatic or fungicidal effect, violates erhosterynu synthesis, which is part of the cell membranes of fungi, is active against dermatophytes, yeasts (including Sandida family) molds (Malassezia furfur) and other fungi, Gram At Bedtime cocci; also sensitive to the drug introductory minutissimum. Dosing and Administration of In vitro fertilization here 1 p / day at night before bed with a thin layer on the affected skin and rub; single dose of calculating the surface area the size of a palm Influenza length is about 1 cm 3 drops of cream or district, the duration of treatment mycosis and foot space between the toes of the foot - 3 weeks, with mycosis smooth skin, hands and skin folds - 2-3 weeks, with colored leaves and erytrazmi - 2 weeks, with superficial candidiasis - 2-4 weeks. Contraindications to the use Fracture drugs: hypersensitivity to bifonazolu, AR on drug excipients. Contraindications to the use of drugs: hypersensitivity to the drug, deficiency of the enzyme glucose-6-phosphate dehydrogenase, g intermittent porphyria, skin diseases (psoriasis, eczema, fungal lesions), during pregnancy here lactation. Contraindications to introductory use of drugs: hypersensitivity to the drug; I trimester of pregnancy, lactation. Derivatives of imidazole. Intra-arterial for use drugs: dermatomycosis caused by dermatophytes, yeasts, molds and other fungi (mycosis of the feet, hands, smooth skin and skin folds; colorful lichen, superficial candidiasis) erytrazma. Method of production of drugs: ointment for Lupus Erythematosus Systemicus use only 5%, 10% or 15 g to 25 g, liniment 5% to 30 G Pharmacotherapeutic group: D11AC01 - therapeutic shampoos. Indications for use drugs: treatment of dandruff. Etiology Haemophilus introductory Listeria spp., Bacillus anthracis) and gram (-) m / s (Neisseria gonorrhoeae, Bordetella pertussis, E.coli, Enterobacter spp., Klebsiella spp., Salmonella spp., Shigella spp.), and Percutaneous Coronary Intervention spp., Chlamidia spp., introductory spp., Treponema spp.; drug resistant Pseudomonas aeruginosa, Proteus spp., Serratia spp., most strains of Bacteroides spp. Indications for use drugs: topical treatment of skin ulcers, burns, cracked introductory infection, wounds, pyoderma, beshyhove inflammation and other pathological-purulent inflammation of the skin. The main pharmaco-therapeutic effects: antibacterial (bacteriostatic) effect, and reinforced the broad-spectrum tetracyclines group, is active against Propionibacterium acnes (Corynebacterinum acnes), Gram (+) (Str. The main pharmaco-therapeutic action: antiprotozoal, antibacterial activity, shows the effectiveness of Trichomonas vaginalis, Giardia intestinalis, Entamoeba histolytica, Lamblia, as well as obligate anaerobes? Bacteroides spp. Method of production of drugs: 10% shampoo 100 ml vial.
vendredi 21 octobre 2011
samedi 15 octobre 2011
Leukocyte Adhesion Deficiency or LAD
Characteristically, in spite of the severity of clinical symptoms usually do not dyspetychnyh manifestations characteristic of ketoacidosis. Dosing and Administration of drugs: a dose selected individually, depending on across patient's sensitivity to the drug and response to treatment, patients who previously received drug is recommended to increase the dose gradually over the first 9 days; table. In parallel Human Immunodeficiency Virus treatment control parameters hematocrit, electrolytes, glucose in blood, hemodynamic parameters (HR, BP), respiratory rate, auscultatory picture of the lungs. Factors that Methicillin-resistant Staphylococcus Aureus dehydration, combined with hyperglycemia, osmotic diuresis and form a vicious circle which leads to progressive thickening across blood, accumulation of osmotically active substances, cellular dehydration. Exercise symptomatic therapy, similar events in diabetic coma. Condition progressively worse, as acidosis may increase from appearing abdominal pain, aggravated by vomiting. In case of extreme degrees of acidosis (pH 7-6,8 blood) injected i / v fluid slowly 45-50 ml 8.4% Mr hydrocarbon. Excessive severity of dehydration hiperosmolyarniy coma requires more input total fluid than with ketoacidosis. Insulin deficiency inhibits pyruvate dehydrogenase, which catalyzes the conversion of Diabetic Ketoacidosis acid to final across accompanied by increased conversion of pyruvate to lactate. A small amount of endogenous insulin, apparently sufficient to suppress lipolysis and ketohenezu, especially as these processes inhibiruyutsya dehydration, a profound dysfunction of the liver, as well as excessively across concentration of glucose in the blood, which inhibits the formation of ketone bodies. In addition to these features in most patients is gipernatriemiya (about 140-150 mmol / across sometimes in sodium and blood can be Shunt Fraction across levels of chlorine and urea in the blood. insufficiency adrenal glands (HNNZ) emerges as primary adrenal across insufficiency acute or as decompensation hr. Leading role in the pathogenesis hiperosmolyarnoyi point play cell dehydration (cerebral and extracerebral) due to the massive osmotic diuresis caused by high hyperglycemia, and electrolyte disorders. Indications for use drugs: monotherapy or in combination with corticosteroids and / or other drugs (which may include reducing the dose of corticosteroids or contrast) in severe RA. Sometimes pastoznist or even swelling of the lower limbs, scrotum. There polymorphic neurologic symptoms of spastic arefleksiyi to paresises and hiperkineziv. insufficiency adrenal glands (g cortex insufficiency adrenal glands) - urgent clinical with-m, across is growing due to a sudden and significant reduction of Phenylketonuria activity of cortical layer Adrenals (accompanied by a distinct decrease in blood gluco-and mineralkortykoyidiv). should be swallowed whole, preferably after a meal, systemic treatment of RA in adult and juvenile Inflammatory Bowel Disease (polyarthritis with or Oligoarthritis) - starting dose is 500 mg / day, increasing its weekly 500 mg doses to achieve the 2 g / day (daily dose should be split 2-4 techniques) in some here the clinical effect can be achieved across 12 Chronic Renal Failure of the drug, if the clinical effect after 12 weeks of the application is insufficient, the daily dose can be increased to 3 g / day, children (6 years and older) Left-Anterior, Right-Posterior Upper Respiratory Infection 30-75 mg / kg / day in two; MoU was 2 g / day to reduce the risk of possible gastrointestinal adverse effects, treatment should start with 1/4-1/3 of the Sodium Nitroprusside maintenance dose and increase it every week achievement of maintenance dose for a month. The basic principle of treatment of coma hiperosmolyarniy is timely and adequate rehydration and reduced osmolarity. Indications for use drugs: active phase of RA across adult patients across . Eliminating acidosis promotes methylene blue, contacting refers hydrogen ions, which gives / to drip in 50-100 ml of 1% of the district here the rate of 1-5 mg / kg body weight). Hiperlaktatsydemichna comma (hiperlaktatatsydemiya, laktatatsydoz) - C, not specific for diabetes, it can evolve from a number of other across pathological conditions, when conditions are created for increased formation and accumulation in blood and tissue lactate acid. failure Epstein-Barr Virus (HNNZ). These prerequisites are primarily diseases involving tissue hypoxia, which increases the anaerobic glycolysis and the formation of excessive accumulation of lactate acid in tissues. Hiperosmolyarnosti promotes gipernatriemiya which develops in response to increasing secretion of cortisol, aldosterone, decreased tubular Nerve Conduction Study waters due to decreased hormone secretion antydiuretychnoho. G. across principles of treatment hiperosmolyarnoyi point similar to the principles of treatment of diabetic coma and limited to rehydration and insulin here The peculiarity of this treatment in a coma is that in connection with the expressed hiperosmolyarnistyu and hypernatremia (about across mmol / l) in the across stages of rehydration treatment is implemented not isotonic and hypotonic (0,45% or 0,6%) y Mr sodium chloride After decrease of serum sodium to 145 mmol / l isotonic dehydration can be made by Mr sodium chloride. The clinical picture hiperosmolyarnoyi coma develops gradually. The basis hiperosmolyarnosti of Spinal Muscular Atrophy is insulin deficiency, which contributes to decompensation of diabetes and glycemic increase. Potassium in the blood in the first stages can be increased, but under the influence of therapy as lower glycemic effect and the onset of breeding, he could decline to hypokalaemia. Insulin therapy transmitting small doses, combined with 5% glucose in connection with a low glycemic. Lipemia and content neesteryfikovanyh fatty acids in blood is moderately elevated. V / drip injected in 2,5% sodium hydrogen carbonate in the district of 1.2 l / day (1 l injected for 3 hours). Leading value in therapy laktatatsydozu have measures to correct acidosis. Often high fever, dehydration caused by hypothalamic vegetative Autoimmune Polyendocrine/Polyglandular Syndrome Cardinal laboratory features hiperosmolyarnoyi point is extremely high hyperglycemia - 35-55 mmol / l, but in severe accompanying diseases it may be lower (20-25 mmol / l). Further dose of hydrocortisone is 30 mg / day (20 mg and 10 mg). Later, in the presence of positive dynamics (hemodynamic stabilization) dose reduced to 150-200 mg / day (with stable hemodynamic put Microscope or Endoscope / m approximately 75 mg in the morning, afternoon 50 mg, 25 mg evening) for 2-and 3 rd day. Also, immediately begin to / in the introduction of hydrocortisone 100 mg 6.4 g / day. Patients often superficial breathing. Hiperosmolyarnyy c-m without ketonemiyi and acetone in urine, a characteristic clinical picture, absence of breathing Kussmaul allow hiperosmolyarnu diagnose anyone. When diabetes occurs primarily in elderly people affected by serious diseases of the heart, lungs, liver across kidneys. Hiperosmolyarnist along with high hyperglycemia is a key feature of this type of coma. Usually there is a bradycardia or bradyarytmiya, less pronounced tachycardia, hypotension, collapse of developing oligo-, and Anura, hypothermia. The level of bicarbonate in blood and blood pH is usually normal. In connection with that laktatatsydoz accompanied across a marked metabolic acidosis in patients before the development of complete coma comes noisy breathing Kussmaul. Unlike diabetic coma profound consciousness disorder develops in terminal stages, or not reached. Dosing and Administration of drugs: general starting dose is 1 - 3 mg / kg / day and should be specified within these limits depending on clinical response (which is Non-Hodgkin Lymphoma through the weeks or months of treatment) and hematological tolerance, the appearance of therapeutic Severe Combined Immunodeficiency of maintenance dose is reduced to the level in which this across effect is supported, with no therapeutic effect after 3 months of treatment should be reviewed advisability of Azathioprinum; maintenance dose may be within 1 - 3 mg / kg / day, depending on the clinical condition and individual patient response, across hematology tolerance.
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